Semen analysis – seminogram and detailed examination

• examine the mobility and concentration of sperm based on several images,
• assess their viability using fluorescence microscopy,
• automatically classify sperm morphological defects.

It is necessary to repeat the semen analysis after the treatment if the result is abnormal. It does not indicate the cause of fertility disorders, nor does it confirm normal fertility. Most often, it is necessary to perform additional tests.

Depending on the result of the basic semen analysis (seminogram), as well as the history and physical examination, the doctor may also order some other additional tests that will indicate possible problems related to male infertility:

• microbiological culture of semen for aerobic and anaerobic bacteria as well as Mycoplasma, Ureaplasma, Chlamydia,
• basic labs: blood count, liver function tests, glucose concentration, lipid profile, urinalysis,
• basic hormonal tests are ordered in the case of a lack of sperm in semen or a reduced number of semen (below 5 million / ml), sexual dysfunction, or suspicion of endocrine diseases. Standard tests are Total Testosterone, LH, FSH, Prolactin, SHBG, Estradiol, Inhibin B, AMH, thyroid hormones.
• chromatin and sperm DNA fragmentation assess the degree of chromatin maturity and the degree of fragmentation of sperm DNA,
• the HBA TEST measures the ability of sperm to bind to hyaluronan, the main extracellular component of the structures surrounding the egg,
• the presence of anti-sperm antibodies (ASA) in semen, e.g., MAR test, is one of the main causes of immunological infertility,
• semen biochemical tests enable the assessment of the main components of the seminal fluid,
• the migration test (SWIM UP) assess the ability of sperm to leave the seminal fluid and enter the woman’s genital tract,
• genetic testing,
• ultrasound examination of the scrotum, testes, and prostate gland.

Chromatin + seminogram – test package: basic seminogram

• Additional test for sperm DNA.
• It assesses the degree of chromatin fragmentation.

SCD (Sperm Chromatin Dispersion) is an analysis of the correct structure of DNA in sperm. It assesses the degree of chromatin fragmentation.

The NAG level correlates with the correct function of the epididymis. The analysis shows whether there is an inflammation in the epididymis and assesses the patency of the epididymis.

The test checks the percentage of sperm showing the ability to bind to hyaluronic acid. The test determines the degree of sperm maturity.

MAR TEST IgG and IgA sperm antibodies determine the percentage of sperm joining to the latex beads coated with antibodies. It verifies whether proteins (antibodies) in the semen cause sperm to stick together, thus preventing their progressive movement.

This sugar level in the semen reflects the proper function of the seminal vesicles. It determines whether there is an inflammation within the organ.

Its level reflects the proper functioning of the prostate gland (prostate). The analysis is used to determine whether there is an inflammation or neoplasm within the gland.

Sperm sample must be collected into a special container. Semen is obtained through masturbation. 2-7 days of sexual abstinence are strongly recommended. Only fresh semen is suitable for testing, so sample must be produced at the clinic. We know it is an embarrassing and intimate procedure, so we provide discreet and comfortable conditions to minimize the stress associated with the examination. If the patient cannot produce a sample at the clinic, he can bring it over. Time from collection to delivery to the laboratory cannot exceed 60 minutes. During transport, the sample should be stored at a temperature close to body temperature. The semen is immediately for analysis.

If the semen analysis shows abnormalities, appropriate treatment is required. Treatment of male factor infertility may include antibiotic therapy for the infection, surgical procedures, and medications to improve sperm quality. In some cases, it is not possible to establish a clear cause for the reduced quality of semen. In such cases, we recommend IUI or IVF.